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Kobayashi T, Ruan S, Clodi K, Kliche KO, Shiku H, Andreeff M , Zhang W

Integrating these research results, GPX4 can be regarded not only as a potential biomarker sensitively reflecting OA pathological severity and disease stage but also as a therapeutically promising target with core protective functions in OA progression

The mutant is not active with ethidium bromide E208K O43708, Q9H4Y5, Q16772, P09211, P09210, P08263, P09488, O15217, P28161, Q03013, P46439, P78417, O60760, Q7RTV2, P21266, P0CG30 naturally occuring mutation, the single E208K substitution alone, created independently of the E155 deletion, does not have a significant impact on activity

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Rickard D.J., et al